Effect of Tectona grandis on phenylhydrazine induced anemia in rats. Higher doses (>500mg/kg) of extract significantly (p<0.05) increased RBC, hemoglobin and platelet compared to the control. Correspondence to Parameter that were determined include total haemoglobin concentration (HGB), packed cell volume (PCV), red blood cell count (RBC), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), mean corpuscular volume (MCV), white blood cell count (WBC), Lymphocyte count (LYM), MID sized cell (MID), Granulocyte Count (GRM) and platelet count (PLT). Star Apple: Amazing Health Benefits of eating its fruits. J Med Plants Res. Too much fertilizer is damaging for your plant. The lush foliage and distinctive flowers make Brazilian Plume a natural for a tropical garden. The genus Justicia named after the 18th-century Scottish botanist James Justice is a flowering plant in the family Acanthaceae. It results from one or more of the following events: loss of red blood cells (RBCs), reduction in the production of RBCs, increased destruction of RBCs, and shorter life span of RBCs (McEvoy, 2013). The efficiency of some preexisting anti-obesity drugs was limited by several adverse effects associated with them including gastrointestinal disorder, high risk of cancer, and long-term use detrimental effects on some organs such as liver, kidney and pancreas [ 4, 8 ]. This is attributed to the anti-hyperlipidaemic properties of the plant. Photomicrograph of a liver sections stained with Haematoxylin and Eosin (Mag. Information from this source is evidence-based and objective, and without commercial influence. long (25 cm), and showy flower plumes, 8 in. Keep in mind that natural products are not always necessarily safe and dosages can be important. Group 2, 3, 4, 5, 6 were respectively administered orally with 50, 100, 500, 800 and 1200mg/kg body weight of JCEE once daily for 14days using an oral gavage. Superoxide dismutase (SOD) activities were elevated across all doses in the liver with significant (p<0.05) difference only observed in the highest dose (1200mg/kg) while kidney showed no significant difference compared to the control. Pinch Justicia carnea plants back after theyve flowered. It is cultivated and sold as a decorative potted plant and is planted in landscaping as a feature plant in warm . The renal cortex showed normal glomeruli with mesangial cells and capsular spaces appeared normal (white arrow), the renal tubules appear normal (blue arrow) and interstitial spaces also observed normal (black arrow). Justicia carnea is commonly cultivated and grown as an ornamental potted plant. So lets go through this together. Justicia carnea needs bright, indirect light to thrive. Despite the use of Justicia carnea and other reported scientific studies, there are no reports on its effects on the major organs of the body. This is . It also can be used in combination with other vegetables such as the Efinrin (scent leaves), ugwu etc. Where, A=absorbance, TV=total volume, SV=sample volume, =extinction coefficient, TP=total protein. He is a research assistant in the Biochemistry Unit of the same Department. Chemical constituents and biological activities of species of Justicia a review. (2020). Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. 2. Join now and start creating your dream garden! J Ethnopharmacol. The leaves are also rich source of vitamin A, vitamin C, and vitamin E. Another plant with this composition is pumpkin fruit. 400). Another health benefit of ewe eje leaves is in cardiac protection and hypolipidemic effect. It is obvious that Justicia carnea has potential antianemic, antioxidant, antidiabetic, hepatoprotective, and immune-boosting properties. Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. Justicia carnea (ewe eje) is used by pregnant women to boost the production of red blood cells and cure anemia in pregnancy. This may be because of its hepatoprotective activity. Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. In subacute study, rats were randomized into six groups of five rats per group: Group 1 (control) received distilled water, group 2, 3, 4, 5, 6 received 50, 100, 500, 800 and 1200mg/kg body weight of J. carnea ethanol extract once daily using oral gavage. 1978;52:30210. This claim by traditional healers with regard to the efficacy of justicia carnea in the treatment diabetes have been researched on and it was found to be true. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. Cut from the stem, some fresh or dried Justicia carnea leaves. View abstract. Authors TSO, KOK and ESA manage experimental protocols and performed the experiments under the supervision of FOA. The presence of blood boosting nutrients such as iron, copper, zinc and vitamin C can help prevent iron-deficiency anaemia and other anemic conditions. Buege JA, Aust SD. 2016;4(1):5360. Ewe eje can increase blood count and volume. J Am Diet Assoc. In various parts of Africa, several species of Justicia are used in traditional medicine for the treatment of anemia, inflammation, fever, diarrhea, liver diseases and arthritis respiratory and gastrointestinal disorder [8, 9]. Keep an eye out for glasshouse red spider mite and glasshouse whitefly. How Justicia Betonica is effective for various diseases is listed in repertory format. It is also composed of vitamins and minerals good for heart health. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. The levels of white blood cell count, lymphocyte, granulocyte and MID could indicate that ethanol extract of J. carnea leaf pose no toxicity or sub acute inflammation to the overall defense mechanism and immunity of the experimental rats. 15 Amazing benefits of brocoli juice and side effects. 50mg/kg-1200mg/kg treatments relative to control showed varied degree of hepatic injury that is dose dependent. Nutritive properties of aqueous extract Justicia carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male wistar albino rats. Despite living in close proximity to this plant, many individuals may be unaware of its benefits. Wash the Justicia carnea leaves thoroughly to eliminate all forms of insects and dust. 2015;174:61827 https://doi.org/10.1016/j.jep.2015.06.005. No observable focal sclerosis of renal glomeruli, capsular spaces around the glomerulus appears normal with distinct layering of renal microcellular structures. With exception of low doses that showed normal morphology of the hepatocyte and sinusoid that is not infiltrated, high doses of extract greater than 500mg/kg showed mild fat congestion in the central venules with liver parenchyma showing area of hemorrhage compared to the control. Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Sci. Ewe eje is a rich source of phytochemicals, minerals and vitamins. These compounds beyond boosting your blood concentration, thereby enhancing the transport of nutrients to various parts of the body, also boost your immune system against several infectious diseases. Note this is the default cart. Not sure which Justicia to pick?Compare All Justicia. Ewe eje or Ewe ajeri is known by the Igbo tribe as Ogwu obara. Clinical Guide to Laboratory tests. Colorimetric assay of catalase. Relative to control, lymphocyte and granulocyte exhibited no significant difference in all doses while MID was elevated in treated groups with significant increase in rats administered with 500 and 800mg/kg body weight. For some, the boiling method is preferred while for others, soaking in hot water is more convenient. Rich on haematological and biochemical parameters in healthy Wistar rats. Acta Sci Pol Technol Aliment. The weight of organs (liver and kidney) reduced steadily in a concentration dependent manner. Create a beautiful garden with this colorful and Use our interactive toolsto design your dream garden. Assessment of Aloe vera (L) genotoxic potential on Escherichia coli and plasmid DNA. Kone WM, Koffi AG, Bomisso EL, Tra Bi FH. Extinction coefficient () of MDA TBA complex=1.56105M1cm1. Consumption of medicinal plants without scrutinizing its efficacy and safety can result in unexpected toxic effects resulting in physiology changes of different organs in the body. It also increases good cholesterol levels. In the study conducted by Onyeabor and his colleagues, it was shown that the leaf extract not only reverses anemic condition, but also lowered the lipid profile of the experimental rats. At the end of 14th day of administration, rats were allowed to fast overnight, sacrificed to collect samples for biochemical analysis and histopathological examination. Justicia carnea does not cause miscarriage or congenital birth defects. Studies have shown that ewe eje isnt capable of causing damage to the liver. Keep the soil moist, but not waterlogged. The aim of this study is to evaluate the effects of J. carnea leaf extract on hematology indices and organ antioxidant system in healthy wistar rats. From mild to severe order, the graded doses showed distorted renal cortex with collapsed renal glomeruli and dillated capsular spaces. One of the symptoms of diabetes is elevated blood glucose level. It has been reported previously that under certain conditions, dietary antioxidants such as ascorbic acid, tocopherol and carotenoids could act, occasionally, as pro-oxidants to initiate slight degree of oxidative stress microenvironment. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. As declared by all authors, no competing interests exist. Liver and kidney are the main targets of toxicants because they are respectively involved in biotransformation and excretion of xenobiotics. The plant possess several bioactive compounds like polyphenols, which act as antioxidants or anti-inflammatory compounds. J Ethnopharmacol. Microsomal lipid peroxidation. Mounanga MB, Mewonob L, Angone SA. It is a creeping, perennial plant and grows up to 2 meters tall. These tropical plants are not very fussy about soil. Catalase activity (U/ml) was measured following the method of Sinha [17]. 3rd ed. Caterpillars may be an occasional problem, chewing down on some of the foliage. [1] The perennial plant is native to the Atlantic Forest ecoregions of eastern Brazil . International Journal of Biochemistry Research & Review. Acute and sub-acute toxicity studies of aqueous and methanol extracts of Nelsonia campestris in rats. However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. Organic extract of Justicia pectoralis Jacq. Akintimehin is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Brazilian-plumeflowers are best propagated from softwood cuttings. However, lowest (50mg/kg) dose of extract significantly elevated MCH and MCHC. Anal Biochem. Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. Cookies policy. Joseph, H., Gleye, J., Moulis, C., Fouraste, I., and Stanislas, E. O-Methoxylated C-glycosylflavones from Justicia pectoralis. Background: Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential.